MolNFT v1 · #108929 · protein
Structure of heme oxygenase-2 containing residues 1-288 lacking the membrane spanning region
4WMH · Heme oxygenase 2: “Structure of heme oxygenase-2 containing residues 1-288 lacking the membrane spanning region”. X-ray diffraction, 1 ligand (CL), 2 pockets (best druggability 0.74). MolNFT v1 #108929 on GenesisL1: 3D structure…
- PDB
- 4WMH
- Type
- protein
- Length
- 207 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Heme oxygenase 2
- EC
- 1.14.99.3
- UniProt
- P30519
- Ligands
- CL
- Pockets
- 2 · best druggability 0.74
Structure
x-ray diffraction · 1 distinct chain · 73% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Heme oxygenase 2 (EC 1.14.99.3) | protein | 207 | 73% helix, 0% strand | P30519 |
Ligands and binding sites
- CL · Chloride ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 367 | 0.74 | 0.84 | 39 | empty |
| 2 | 88 | 0.48 | 0.82 | 24 | empty |
Compared structures
- 4WMH · Structure of heme oxygenase-2 containing residues 1-288 lacking the membrane spanning… · the same entry in another collection · chain A against A, TM-score 1.00
- P30519 · AlphaFold monomer V2.0 prediction for heme oxygenase 2 (P30519) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P30519
- Elsewhere: RCSB PDB 4WMH · PDBe 4WMH · UniProt P30519
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