UniProt P30519
Heme oxygenase 2 (P30519)
Heme oxygenase 2 (UniProt P30519), EC 1.14.14.18: 14 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P30519
- Protein
- Heme oxygenase 2
- EC
- 1.14.14.18
- Experimental structures
- 14
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 15 · 2 records with a druggable one
Structures
15 records of P30519 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2Q32 | Crystal structure of human heme oxygenase-2 C127A (HO-2) | x-ray diffraction | A, B | — | — |
| 2Q32 | Crystal structure of human heme oxygenase-2 C127A (ho-2) | x-ray diffraction | A, B | — | — |
| 2QPP | Crystal structure of human heme oxygenase-2 C127A (HO-2) with bound heme | x-ray diffraction | A, B | — | — |
| 2QPP | Crystal structure of human heme oxygenase-2 C127A (ho-2) with bound heme | x-ray diffraction | A, B | — | — |
| 2RGZ | Ensemble refinement of the protein crystal structure of human heme oxygenase-2 C127A (HO-2) with… | x-ray diffraction | A, B | — | — |
| 2RGZ | Ensemble refinement of the protein crystal structure of human heme oxygenase-2 C127A (ho-2) with… | x-ray diffraction | A, B | — | — |
| 4WMH | Structure of heme oxygenase-2 containing residues 1-288 lacking the membrane spanning region | x-ray diffraction | A | — | — |
| 4WMH | Structure of heme oxygenase-2 containing residues 1-288 lacking the membrane spanning region | x-ray diffraction | A | — | — |
| 5UC8 | Crystal structure of human Heme Oxygenase-2 | x-ray diffraction | A, B, C, D | — | 8 (best 0.76) |
| 5UC8 | Crystal structure of human heme oxygenase-2 | x-ray diffraction | A, B, C, D | — | — |
| 5UC9 | Crystal structure of human Heme Oxygenase-2 in complex with Myristate | x-ray diffraction | A, B, C, D | MYR | — |
| 5UC9 | Crystal structure of human heme oxygenase-2 in complex with myristate | x-ray diffraction | A, B, C, D | MYR | — |
| 5UCA | Crystal structure of human Heme Oxygenase-2 in complex with Laurate | x-ray diffraction | A, B, C, D | DAO | 7 (best 0.77) |
| 5UCA | Crystal structure of human heme oxygenase-2 in complex with laurate | x-ray diffraction | A, B, C, D | DAO | — |
| P30519 | AlphaFold monomer V2.0 prediction for heme oxygenase 2 (P30519) | predicted | A | — | — |
Ligands
Experiment against prediction
- 2QPP chain A against the predicted model P30519: TM-score 1.00, RMSD 0.36 Å
- 2QPP chain A against the predicted model P30519: TM-score 1.00, RMSD 0.36 Å
- 5UC9 chain C against the predicted model P30519: TM-score 0.99, RMSD 0.41 Å
- 5UC9 chain C against the predicted model P30519: TM-score 0.99, RMSD 0.41 Å
- 5UCA chain B against the predicted model P30519: TM-score 0.99, RMSD 0.43 Å
- 5UCA chain B against the predicted model P30519: TM-score 0.99, RMSD 0.43 Å
- 5UCA chain A against the predicted model P30519: TM-score 0.99, RMSD 0.43 Å
- 5UCA chain A against the predicted model P30519: TM-score 0.99, RMSD 0.43 Å
- 2Q32 chain A against the predicted model P30519: TM-score 0.99, RMSD 0.43 Å
- 2Q32 chain A against the predicted model P30519: TM-score 0.99, RMSD 0.43 Å
Elsewhere
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