MolNFT v1 · #108889 · protein
Structure of dextran glucosidase with glucose
4WLC · Glucan 1,6-alpha-glucosidase: “Structure of dextran glucosidase with glucose”. X-ray diffraction, 2 ligands (BGC, CA), 3 pockets (best druggability 0.71). MolNFT v1 #108889 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 4WLC
- Type
- protein
- Length
- 536 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glucan 1,6-alpha-glucosidase
- EC
- 3.2.1.70
- UniProt
- Q99040
- Ligands
- BGC, CA
- Pockets
- 3 · best druggability 0.71
Structure
x-ray diffraction · 1 distinct chain · 34% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Glucan 1,6-alpha-glucosidase (EC 3.2.1.70) | protein | 536 | 34% helix, 18% strand | Q99040 |
Ligands and binding sites
- BGC · beta-D-glucopyranose · sugar · chains A
- CA · Calcium ion · metal · 3 copies · chains A
- GOL · Glycerol · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 523 | 0.71 | 0.80 | 47 | BGC, GOL |
| 2 | 133 | 0.56 | 0.83 | 23 | empty |
| 3 | 64 | 0.42 | 0.81 | 14 | empty |
Modifications
Observed in the structure: 1 glycan (glycosylation).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q99040
- Elsewhere: RCSB PDB 4WLC · PDBe 4WLC · UniProt Q99040
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