MolNFT v1 · #108877 · protein
Complex of autonomous scag cohesin cohg and X-doc domains
4WKZ · Putative cellulose-binding protein: “Complex of autonomous scag cohesin cohg and X-doc domains”. X-ray diffraction, 2 ligands (CA, NO3), 5 pockets (best druggability 0.48). MolNFT v1 #108877 on GenesisL1: 3D structure, binding sites…
- PDB
- 4WKZ
- Type
- protein
- Length
- 415 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative cellulose-binding protein; Autonomous cohesin
- UniProt
- A0AEF5, W5IDC3
- Ligands
- CA, NO3
- Pockets
- 5 · best druggability 0.48
Structure
x-ray diffraction · 2 distinct chains · 23% helix, 33% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Putative cellulose-binding protein | protein | 231 | 31% helix, 26% strand | A0AEF5 |
| B | Autonomous cohesin | protein | 184 | 13% helix, 41% strand | W5IDC3 |
Ligands and binding sites
- CA · Calcium ion · metal · 2 copies · chains A
- NO3 · Nitrate ion · ion · chains A, B
- ACT · Acetate ion · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 96 | 0.48 | 0.81 | 17 | empty |
| 2 | 109 | 0.38 | 0.75 | 20 | empty |
| 3 | 64 | 0.35 | 0.77 | 16 | empty |
| 4 | 81 | 0.34 | 0.75 | 18 | empty |
| 5 | 88 | 0.33 | 0.73 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 928 Ų buried · 9 hydrogen bonds · protein-protein
Compared structures
- 4WKZ · Complex of autonomous ScaG cohesin CohG and X-doc domains · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0AEF5
- Every structure of UniProt W5IDC3
- Elsewhere: RCSB PDB 4WKZ · PDBe 4WKZ · UniProt A0AEF5 · UniProt W5IDC3
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.