MolNFT v1 · #108839 · protein
Crystal structure of RSA4 from saccharomyces cerevisiae
4WJU · Ribosome assembly protein 4: “Crystal structure of RSA4 from saccharomyces cerevisiae”. X-ray diffraction, 11 pockets (best druggability 0.82). MolNFT v1 #108839 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4WJU
- Type
- protein
- Length
- 903 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ribosome assembly protein 4
- UniProt
- P25382
- Pockets
- 11 · best druggability 0.82
Structure
x-ray diffraction · 2 distinct chains · 9% helix, 43% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ribosome assembly protein 4 | protein | 457 | 9% helix, 42% strand | P25382 |
| B | Ribosome assembly protein 4 | protein | 446 | 9% helix, 44% strand | P25382 |
Ligands and binding sites
- GOL · Glycerol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
11 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 939 | 0.82 | 0.83 | 63 | empty |
| 2 | 993 | 0.81 | 0.82 | 57 | empty |
| 3 | 331 | 0.65 | 0.80 | 38 | empty |
| 4 | 310 | 0.60 | 0.78 | 36 | empty |
| 5 | 216 | 0.54 | 0.78 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 501 Ų buried · 8 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P25382
- Elsewhere: RCSB PDB 4WJU · PDBe 4WJU · UniProt P25382
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