UniProt P25382
Ribosome assembly protein 4 (P25382)
Ribosome assembly protein 4 (UniProt P25382): 19 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 78 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P25382
- Protein
- Ribosome assembly protein 4
- Experimental structures
- 19
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 78 · 18 records with a druggable one
Structures
20 records of P25382 in the MolNFT archive: 19 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3JCT | Cryo-em structure of eukaryotic pre-60S ribosomal subunits | electron microscopy | x | — | 1 (best 0.86) |
| 4V7F | Arx1 pre-60S particle. | electron microscopy | q | — | 1 (best 0.65) |
| 4V7F | ARX1 pre-60S particle. | electron microscopy | q | — | 1 (best 0.65) |
| 4WJU | Crystal structure of Rsa4 from Saccharomyces cerevisiae | x-ray diffraction | A, B | — | 11 (best 0.82) |
| 4WJU | Crystal structure of RSA4 from saccharomyces cerevisiae | x-ray diffraction | A, B | — | 11 (best 0.82) |
| 4WJV | Crystal structure of Rsa4 in complex with the Nsa2 binding peptide | x-ray diffraction | A, B, C, D | SO4 | 16 (best 0.88) |
| 4WJV | Crystal structure of RSA4 in complex with the NSA2 binding peptide | x-ray diffraction | A, B, C, D | SO4 | 16 (best 0.88) |
| 5JCS | Cryo-EM structure of the RIX1-REA1 pre-60S particle | electron microscopy | q | — | — |
| 6FT6 | Structure of the Nop53 pre-60S particle bound to the exosome nuclear cofactors | electron microscopy | x | — | 2 (best 0.86) |
| 6M62 | Cryo-Em structure of eukaryotic pre-60S ribosome subunit from Saccharomyces cerevisiae rpf2 delta… | electron microscopy | x | — | 1 (best 0.86) |
| 6YLF | Rix1-Rea1 pre-60S particle - Rea1, body 3 (rigid body refinement, composite structure of Rea1 ring… | electron microscopy | xP1 | — | — |
| 6YLG | Rix1-Rea1 pre-60S particle - 60S core, body 1 (rigid body refinement) | electron microscopy | x | — | 1 (best 0.87) |
| 6YLH | Rix1-Rea1 pre-60S particle - full composite structure | electron microscopy | x | — | 1 (best 0.88) |
| 7BT6 | Cryo-EM structure of pre-60S ribosome from Saccharomyces cerevisiae rpl4delta63-87 strain at 3.12… | electron microscopy | x | — | 2 (best 0.86) |
| 7BTB | Cryo-EM structure of pre-60S ribosome from Saccharomyces cerevisiae rpl4delta63-87 strain at 3.22… | electron microscopy | x | — | 1 (best 0.86) |
| 7OH3 | Nog1-TAP associated immature ribosomal particle population B from S. cerevisiae | electron microscopy | x | — | 1 (best 0.87) |
| 7OHQ | Nog1-TAP associated immature ribosomal particle population C from S. cerevisiae | electron microscopy | x | — | 1 (best 0.87) |
| 7OHT | Nog1-TAP associated immature ribosomal particles from S. cerevisiae after rpL2 expression shut… | electron microscopy | x | — | 5 (best 0.87) |
| 7UG6 | Cryo-EM structure of pre-60S ribosomal subunit, unmethylated G2922 | electron microscopy | x | — | 1 (best 0.86) |
| P25382 | AlphaFold monomer V2.0 prediction for ribosome assembly protein 4 (P25382) | predicted | A | — | 5 (best 0.83) |
Ligands
- SO4 · Sulfate ion · in 2 records
Experiment against prediction
- 4WJV chain A against the predicted model P25382: TM-score 0.99, RMSD 0.62 Å
- 4WJV chain A against the predicted model P25382: TM-score 0.99, RMSD 0.62 Å
- 6YLG chain x against the predicted model P25382: TM-score 0.99, RMSD 0.69 Å
- 4WJU chain B against the predicted model P25382: TM-score 0.98, RMSD 1.01 Å
- 4WJU chain B against the predicted model P25382: TM-score 0.98, RMSD 1.01 Å
- 6M62 chain x against the predicted model P25382: TM-score 0.96, RMSD 1.51 Å
- 7OHQ chain x against the predicted model P25382: TM-score 0.96, RMSD 1.87 Å
- 7OH3 chain x against the predicted model P25382: TM-score 0.95, RMSD 2.10 Å
- 7UG6 chain x against the predicted model P25382: TM-score 0.95, RMSD 2.13 Å
- 6FT6 chain x against the predicted model P25382: TM-score 0.95, RMSD 2.21 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.