MolNFT v1 · #108315 · protein

Apo-structure of ALPHA2,3-sialyltransferase variant 1 from pasteurella dagmatis

4V38: “Apo-structure of ALPHA2,3-sialyltransferase variant 1 from pasteurella dagmatis”. X-ray diffraction, 4 pockets (best druggability 0.53). MolNFT v1 #108315 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4V38
Type: protein
Length: 388 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Sialyltransferase
UniProt: K9UUI6
Pockets: 4 · best druggability 0.53

Structure

x-ray diffraction · 1 distinct chain · 41% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Sialyltransferase	protein	388	41% helix, 19% strand	K9UUI6

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	263	0.53	0.76	41	empty
2	83	0.43	0.79	14	empty
3	52	0.43	0.83	14	empty
4	63	0.32	0.76	17	empty

Compared structures

4V38 · Apo-structure of alpha2,3-sialyltransferase variant 1 from Pasteurella dagmatis · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt K9UUI6
Elsewhere: RCSB PDB 4V38 · PDBe 4V38 · UniProt K9UUI6

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