MolNFT v1 · #108190 · protein

Structure of the wnt deacylase notum - crystal form VIII - phosphate complex - 2.4A

4UZA · Protein notum homolog: “Structure of the wnt deacylase notum - crystal form VIII - phosphate complex - 2.4A”. X-ray diffraction, 2 ligands (NAG, PO4), 1 pocket (best druggability 0.74). MolNFT v1 #108190 on GenesisL1: 3D structure…

PDB: 4UZA
Type: protein
Length: 355 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein notum homolog
EC: 3.1.1.1
UniProt: Q6P988
Ligands: NAG, PO4
Pockets: 1 · best druggability 0.74

Structure

x-ray diffraction · 1 distinct chain · 33% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein notum homolog (EC 3.1.1.1)	protein	355	33% helix, 17% strand	Q6P988

Ligands and binding sites

NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · chains A
PO4 · Phosphate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	80	0.74	0.97	14	empty

Modifications

Observed in the structure: 7 disulfide, 1 glycan (disulfide, N-glycosylation).

Compared structures

4UZA · Structure of the wnt deacylase notum - crystal form VIII - phosphate complex - 2.4A · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6P988
Elsewhere: RCSB PDB 4UZA · PDBe 4UZA · UniProt Q6P988

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