MolNFT v1 · #107968 · protein

The X-ray structure of calcium bound human sorcin

4USL: “The X-ray structure of calcium bound human sorcin”. X-ray diffraction, 2 ligands (CA, SO4), 1 pocket (best druggability 0.26). MolNFT v1 #107968 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4USL
Type: protein
Length: 179 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Sorcin
UniProt: P30626
Ligands: CA, SO4
Pockets: 1 · best druggability 0.26

Structure

x-ray diffraction · 2 distinct chains · 60% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Sorcin	protein	173	62% helix, 2% strand	P30626
D	Sorcin	protein	6	0% helix, 0% strand	P30626

Ligands and binding sites

CA · Calcium ion · metal · 3 copies · chains A
SO4 · Sulfate ion · ion · chains A
PEG · Di(hydroxyethyl)ether · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	54	0.26	0.72	14	empty

Interfaces

1 interface between chains.

A–D · 426 Å² buried · 4 hydrogen bonds · protein-protein

Compared structures

4USL · The X-ray structure of calcium bound human sorcin · the same entry in another collection · chain A against A, TM-score 1.00
P30626 · AlphaFold monomer V2.0 prediction for sorcin (P30626) · a predicted model of the same protein · chain A against A, TM-score 0.75

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P30626
Elsewhere: RCSB PDB 4USL · PDBe 4USL · UniProt P30626

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