MolNFT v1 · #107801 · protein
Human insulin B26ASN mutant crystal structure
4UNG · Insulin a chain: “Human insulin B26ASN mutant crystal structure”. X-ray diffraction, 1 ligand (SO4). MolNFT v1 #107801 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4UNG
- Type
- protein
- Length
- 98 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Insulin a chain; Insulin B chain
- UniProt
- P01308
- Ligands
- SO4
Structure
x-ray diffraction · 2 distinct chains · 55% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C | Insulin a chain | protein | 21 | 62% helix, 0% strand | P01308 |
| B, D | Insulin B chain | protein | 28 | 50% helix, 0% strand | P01308 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · chains C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
6 interfaces between chains.
- C–D · 586 Ų buried · 11 hydrogen bonds · protein-protein
- A–B · 558 Ų buried · 11 hydrogen bonds · protein-protein
- A–D · 340 Ų buried · 3 hydrogen bonds · protein-protein
- B–C · 255 Ų buried · 1 hydrogen bond · protein-protein
- A–C · 157 Ų buried · 0 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 6 disulfide (disulfide).
Compared structures
- 4UNG · Human insulin B26Asn mutant crystal structure · the same entry in another collection · chain C against C, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P01308
- Elsewhere: RCSB PDB 4UNG · PDBe 4UNG · UniProt P01308
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