MolNFT v1 · #10769 · protein

Crystal structure of human pirin: a BCL-3 and nuclear factor I interacting protein and a cupin superfamily member

1J1L: “Crystal structure of human pirin: a BCL-3 and nuclear factor I interacting protein and a cupin superfamily…”. X-ray diffraction, 1 ligand (FE2), 1 pocket (best druggability 0.48). MolNFT v1 #10769 on GenesisL1: 3D structure, binding…

PDB: 1J1L
Type: protein
Length: 288 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Pirin
UniProt: O00625
Ligands: FE2
Pockets: 1 · best druggability 0.48

Structure

x-ray diffraction · 1 distinct chain · 7% helix, 48% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Pirin	protein	288	7% helix, 48% strand	O00625

Ligands and binding sites

FE2 · Fe (II) ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	121	0.48	0.79	20	empty

Modifications

Observed in the structure: 6 modified (engineered).

Compared structures

1J1L · Crystal structure of human Pirin: a Bcl-3 and Nuclear factor I interacting protein and a… · the same entry in another collection · chain A against A, TM-score 1.00
O00625 · AlphaFold monomer V2.0 prediction for pirin (O00625) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O00625
Elsewhere: RCSB PDB 1J1L · PDBe 1J1L · UniProt O00625

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