MolNFT v1 · #106836 · protein
Structure of ephrin type-a receptor 2
4TRL: “Structure of ephrin type-a receptor 2”. X-ray diffraction, 3 pockets (best druggability 0.62). MolNFT v1 #106836 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4TRL
- Type
- protein
- Length
- 269 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ephrin type-a receptor 2
- EC
- 2.7.10.1
- UniProt
- P29317
- Pockets
- 3 · best druggability 0.62
Structure
x-ray diffraction · 1 distinct chain · 38% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ephrin type-a receptor 2 (EC 2.7.10.1) | protein | 269 | 38% helix, 19% strand | P29317 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 307 | 0.62 | 0.79 | 38 | empty |
| 2 | 109 | 0.44 | 0.78 | 19 | empty |
| 3 | 52 | 0.29 | 0.75 | 14 | empty |
Modifications
Observed in the structure: 1 modified (phosphorylation).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P29317
- Elsewhere: RCSB PDB 4TRL · PDBe 4TRL · UniProt P29317
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