MolNFT v1 · #106492 · protein

Wild type T4 lysozyme structure

4S0W: “Wild type T4 lysozyme structure”. X-ray diffraction, 2 ligands (SO4, CL), 1 pocket (best druggability 0.79). MolNFT v1 #106492 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4S0W
Type: protein
Length: 324 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Lysozyme
EC: 3.2.1.17
UniProt: D9IEF7
Ligands: SO4, CL
Pockets: 1 · best druggability 0.79

Structure

x-ray diffraction · 1 distinct chain · 62% helix, 9% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Lysozyme (EC 3.2.1.17)	protein	162	62% helix, 9% strand	D9IEF7

Ligands and binding sites

SO4 · Sulfate ion · ion · 4 copies · chains A, B
CL · Chloride ion · ion · 3 copies · chains A, B
GOL · Glycerol · additive · 3 copies · chains A, B
EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid · additive · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1118	0.79	0.81	80	EPE, CL

Interfaces

1 interface between chains.

A–B · 803 Å² buried · 16 hydrogen bonds · protein-protein

Compared structures

4S0W · Wild type T4 lysozyme structure · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt D9IEF7
Elsewhere: RCSB PDB 4S0W · PDBe 4S0W · UniProt D9IEF7

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