MolNFT v1 · #106444 · protein

Pre-mRNA-splicing factor 38A as 1-179

4RZ9: “Pre-mRNA-splicing factor 38A as 1-179”. X-ray diffraction, 2 pockets (best druggability 0.39). MolNFT v1 #106444 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4RZ9
Type: protein
Length: 179 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Pre-mRNA-splicing factor 38A
UniProt: Q8NAV1
Pockets: 2 · best druggability 0.39

Structure

x-ray diffraction · 1 distinct chain · 50% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Pre-mRNA-splicing factor 38A	protein	179	50% helix, 12% strand	Q8NAV1

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	92	0.39	0.77	16	empty
2	61	0.35	0.78	13	empty

Compared structures

4RZ9 · Pre-mRNA-splicing factor 38A AS 1-179 · the same entry in another collection · chain A against A, TM-score 1.00
Q8NAV1 · AlphaFold monomer V2.0 prediction for pre-mRNA-splicing factor 38A (Q8NAV1) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8NAV1
Elsewhere: RCSB PDB 4RZ9 · PDBe 4RZ9 · UniProt Q8NAV1

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