MolNFT v1 · #106427 · protein

Crystal structure of the green fluorescent rotein nowgfp (the variant of cyan cerulean) at pH 4.8

4RYS: “Crystal structure of the green fluorescent rotein nowgfp (the variant of cyan cerulean) at pH 4.8”. X-ray diffraction, 1 ligand (CRF), 2 pockets (best druggability 0.81). MolNFT v1 #106427 on GenesisL1: 3D structure, binding sites…

PDB: 4RYS
Type: protein
Length: 229 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Nowgfp
Ligands: CRF
Pockets: 2 · best druggability 0.81

Structure

x-ray diffraction · 1 distinct chain · 12% helix, 51% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nowgfp	protein	229	12% helix, 51% strand	—

Ligands and binding sites

CRF · [(4Z)-2-[(1R,2R)-1-amino-2-hydroxypropyl]-4-(1H-indol-3-ylmethylidene)-5-oxo-4,5-dihydro-1H-imidazol-1-yl]acetic acid · ligand · chains A
GOL · Glycerol · additive · 6 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	181	0.81	0.96	29	CRF
2	106	0.41	0.76	19	empty

Modifications

Observed in the structure: 2 covalent (covalent ligand).

Compared structures

4RYS · Crystal structure of the green fluorescent rotein NowGFP (the variant of cyan Cerulean)… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 4RYS · PDBe 4RYS

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.