MolNFT v1 · #106225 · protein

The structure of the effector protein from pseudomonas syringae pv. syringae strain 61

4RSW · HOPA1: “The structure of the effector protein from pseudomonas syringae pv. syringae strain 61”. X-ray diffraction, 7 pockets (best druggability 0.79). MolNFT v1 #106225 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4RSW
Type: protein
Length: 510 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: HOPA1
UniProt: Q83YM3
Pockets: 7 · best druggability 0.79

Structure

x-ray diffraction · 1 distinct chain · 47% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	HOPA1	protein	255	47% helix, 19% strand	Q83YM3

Pockets

7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	111	0.79	0.98	22	empty
2	142	0.60	0.84	24	empty
3	314	0.59	0.78	53	empty
4	142	0.58	0.83	25	empty
5	77	0.45	0.81	21	empty

Interfaces

1 interface between chains.

A–B · 1700 Å² buried · 33 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 18 modified (engineered).

Compared structures

4RSW · The structure of the effector protein from Pseudomonas syringae pv. syringae strain 61 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q83YM3
Elsewhere: RCSB PDB 4RSW · PDBe 4RSW · UniProt Q83YM3

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