MolNFT v1 · #106003 · protein
The crystal structure of the versatile cytochrome P450 enzyme CYP109B1 from bacillus subtilis
4RM4: “The crystal structure of the versatile cytochrome P450 enzyme CYP109B1 from bacillus subtilis”. X-ray diffraction, 1 ligand (HEM), 2 pockets (best druggability 0.80). MolNFT v1 #106003 on GenesisL1: 3D structure, binding sites and…
- PDB
- 4RM4
- Type
- protein
- Length
- 364 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cytochrome P450
- EC
- 1.14.-.-
- UniProt
- O34374
- Ligands
- HEM
- Pockets
- 2 · best druggability 0.80
Structure
x-ray diffraction · 1 distinct chain · 54% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cytochrome P450 (EC 1.14.-.-) | protein | 364 | 54% helix, 12% strand | O34374 |
Ligands and binding sites
- HEM · Protoporphyrin IX containing Fe · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 876 | 0.80 | 0.83 | 80 | HEM |
| 2 | 64 | 0.31 | 0.75 | 16 | empty |
Compared structures
- 4RM4 · The crystal structure of the versatile cytochrome P450 enzyme CYP109B1 from Bacillus… · the same entry in another collection · chain A against A, TM-score 1.00
- O34374 · AlphaFold monomer V2.0 prediction for putative cytochrome P450 yjib (O34374) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O34374
- Elsewhere: RCSB PDB 4RM4 · PDBe 4RM4 · UniProt O34374
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