Research workbench

The crystal structure of the versatile cytochrome P450 enzyme CYP109B1 from bacillus subtilis

Analyse The crystal structure of the versatile cytochrome P450 enzyme CYP109B1 from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4RM4
Type: protein
Length: 364 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cytochrome P450
EC: 1.14.-.-
UniProt: O34374
Ligands: HEM
Pockets: 2 · best druggability 0.80

Structure

x-ray diffraction · 1 distinct chain · 54% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cytochrome P450 (EC 1.14.-.-)	protein	364	54% helix, 12% strand	O34374

Ligands and binding sites

HEM · Protoporphyrin IX containing Fe · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	876	0.80	0.83	80	HEM
2	64	0.31	0.75	16	empty

Compared structures

4RM4 · The crystal structure of the versatile cytochrome P450 enzyme CYP109B1 from Bacillus… · the same entry in another collection · chain A against A, TM-score 1.00
O34374 · AlphaFold monomer V2.0 prediction for putative cytochrome P450 yjib (O34374) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O34374
Elsewhere: RCSB PDB 4RM4 · PDBe 4RM4 · UniProt O34374

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.