MolNFT v1 · #105947 · protein

Crystal structure of sliding beta clamp from helicobacter pylori

4RKI · DNA polymerase III subunit beta: “Crystal structure of sliding beta clamp from helicobacter pylori”. X-ray diffraction, 3 pockets (best druggability 0.47). MolNFT v1 #105947 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 4RKI
Type: protein
Length: 374 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: DNA polymerase III subunit beta
EC: 2.7.7.7
UniProt: O25242
Pockets: 3 · best druggability 0.47

Structure

x-ray diffraction · 1 distinct chain · 20% helix, 40% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA polymerase III subunit beta (EC 2.7.7.7)	protein	374	20% helix, 40% strand	O25242

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	123	0.47	0.79	19	empty
2	69	0.35	0.76	18	empty
3	60	0.26	0.72	14	empty

Compared structures

4RKI · Crystal structure of sliding beta clamp from Helicobacter pylori · the same entry in another collection · chain A against A, TM-score 1.00
O25242 · AlphaFold monomer V2.0 prediction for beta sliding clamp (O25242) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O25242
Elsewhere: RCSB PDB 4RKI · PDBe 4RKI · UniProt O25242

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