UniProt O25242
DNA polymerase III subunit beta (O25242)
DNA polymerase III subunit beta (UniProt O25242), EC 2.7.7.7: 12 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 19 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- O25242
- Protein
- DNA polymerase III subunit beta
- EC
- 2.7.7.7
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 19 · 2 records with a druggable one
Structures
13 records of O25242 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4RKI | Crystal structure of sliding beta clamp from Helicobacter pylori | x-ray diffraction | A | — | — |
| 4RKI | Crystal structure of sliding beta clamp from helicobacter pylori | x-ray diffraction | A | — | — |
| 5FRQ | Crystal Structure of Helicobacter pylori beta clamp bound to DNA ligase peptide | x-ray diffraction | A, B, C, D | — | 17 (best 0.82) |
| 5FRQ | Crystal structure of helicobacter pylori beta clamp bound to DNA ligase peptide | x-ray diffraction | A, B, C, D | — | — |
| 5FVE | Crystal Structure of Helicobacter pylori beta clamp in complex with 3, 4-Difluorobenzamide | x-ray diffraction | A | 2HO | — |
| 5FVE | Crystal structure of helicobacter pylori beta clamp in complex with 3, 4-difluorobenzamide | x-ray diffraction | A | — | — |
| 5FXT | Crystal Structure of Helicobacter pylori beta clamp in complex with Carprofen | x-ray diffraction | A | 0LA | 2 (best 0.51) |
| 5FXT | Crystal structure of helicobacter pylori beta clamp in complex with carprofen | x-ray diffraction | A | — | — |
| 5G48 | H.pylori Beta clamp in complex with Diflunisal | x-ray diffraction | A, B | 1FL | — |
| 5G48 | H.PYLORI beta clamp in complex with diflunisal | x-ray diffraction | A, B | — | — |
| 5G4Q | H.pylori Beta clamp in complex with 5-chloroisatin | x-ray diffraction | A, B | 2HQ | — |
| 5G4Q | H.PYLORI beta clamp in complex with 5-chloroisatin | x-ray diffraction | A, B | — | — |
| O25242 | AlphaFold monomer V2.0 prediction for beta sliding clamp (O25242) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5FRQ chain A against the predicted model O25242: TM-score 0.99, RMSD 0.68 Å
- 5FRQ chain A against the predicted model O25242: TM-score 0.99, RMSD 0.68 Å
- 5FRQ chain B against the predicted model O25242: TM-score 0.99, RMSD 0.70 Å
- 5FRQ chain B against the predicted model O25242: TM-score 0.99, RMSD 0.70 Å
- 5FRQ chain C against the predicted model O25242: TM-score 0.99, RMSD 0.71 Å
- 5FRQ chain C against the predicted model O25242: TM-score 0.99, RMSD 0.71 Å
- 5FRQ chain D against the predicted model O25242: TM-score 0.99, RMSD 0.67 Å
- 5FRQ chain D against the predicted model O25242: TM-score 0.99, RMSD 0.67 Å
- 5FVE chain A against the predicted model O25242: TM-score 0.98, RMSD 1.03 Å
- 5FVE chain A against the predicted model O25242: TM-score 0.98, RMSD 1.03 Å
Elsewhere
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