MolNFT v1 · #105872 · protein
Crystal structure of CRY23AA1 and CRY37AA1 binary protein complex
4RHZ: “Crystal structure of CRY23AA1 and CRY37AA1 binary protein complex”. X-ray diffraction, 2 ligands (ZN, CA), 3 pockets (best druggability 0.37). MolNFT v1 #105872 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4RHZ
- Type
- protein
- Length
- 384 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- CRY23AA1; CRY37AA1
- UniProt
- Q9KKG8, Q9KKG7
- Ligands
- ZN, CA
- Pockets
- 3 · best druggability 0.37
Structure
x-ray diffraction · 2 distinct chains · 7% helix, 62% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | CRY23AA1 | protein | 259 | 9% helix, 67% strand | Q9KKG8 |
| B | CRY37AA1 | protein | 125 | 2% helix, 53% strand | Q9KKG7 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 61 | 0.37 | 0.79 | 18 | empty |
| 2 | 60 | 0.35 | 0.78 | 15 | empty |
| 3 | 66 | 0.27 | 0.72 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 827 Ų buried · 16 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 4RHZ · Crystal structure of Cry23Aa1 and Cry37Aa1 binary protein complex · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9KKG8
- Every structure of UniProt Q9KKG7
- Elsewhere: RCSB PDB 4RHZ · PDBe 4RHZ · UniProt Q9KKG8 · UniProt Q9KKG7
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