MolNFT v1 · #105826 · protein
Crystal structure of uncharacterized CRISPR/CAS system-associated protein CSM6 from streptococcus mutans
4RGP · CSM6_III-a: “Crystal structure of uncharacterized CRISPR/CAS system-associated protein CSM6 from streptococcus mutans”. X-ray diffraction, 1 ligand (CA), 3 pockets (best druggability 0.74). MolNFT v1 #105826 on GenesisL1: 3D…
- PDB
- 4RGP
- Type
- protein
- Length
- 510 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- CSM6_III-a
- UniProt
- I6U2G5
- Ligands
- CA
- Pockets
- 3 · best druggability 0.74
Structure
x-ray diffraction · 1 distinct chain · 67% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | CSM6_III-a | protein | 255 | 67% helix, 2% strand | I6U2G5 |
Ligands and binding sites
- CA · Calcium ion · metal · 7 copies · chains A, B
- GOL · Glycerol · additive · 2 copies · chains B
- PGE · Triethylene glycol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 878 | 0.74 | 0.78 | 67 | CA |
| 2 | 62 | 0.71 | 0.97 | 23 | empty |
| 3 | 59 | 0.70 | 0.97 | 20 | empty |
Interfaces
1 interface between chains.
- A–B · 2030 Ų buried · 22 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 8 modified (engineered).
Compared structures
- 4RGP · Crystal Structure of Uncharacterized CRISPR/Cas System-associated Protein Csm6 from… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt I6U2G5
- Elsewhere: RCSB PDB 4RGP · PDBe 4RGP · UniProt I6U2G5
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.