MolNFT v1 · #105759 · protein
Mutant ribosomal protein L1 from thermus thermophilus with threonine 217 replaced by valine
4REO · 50S ribosomal protein L1: “Mutant ribosomal protein L1 from thermus thermophilus with threonine 217 replaced by valine”. X-ray diffraction, 2 ligands (GLY, SO4), 2 pockets (best druggability 0.71). MolNFT v1 #105759 on GenesisL1: 3D…
- PDB
- 4REO
- Type
- protein
- Length
- 221 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 50S ribosomal protein L1
- UniProt
- P27150
- Ligands
- GLY, SO4
- Pockets
- 2 · best druggability 0.71
Structure
x-ray diffraction · 1 distinct chain · 36% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 50S ribosomal protein L1 | protein | 221 | 36% helix, 22% strand | P27150 |
Ligands and binding sites
- GLY · Glycine · ligand · 3 copies · chains A
- SO4 · Sulfate ion · ion · 4 copies · chains A
- MPD · (4S)-2-methyl-2,4-pentanediol · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 436 | 0.71 | 0.82 | 54 | MPD |
| 2 | 99 | 0.52 | 0.82 | 20 | empty |
Compared structures
- 4REO · Mutant ribosomal protein l1 from thermus thermophilus with threonine 217 replaced by… · the same entry in another collection · chain A against A, TM-score 1.00
- P27150 · AlphaFold monomer V2.0 prediction for 50S ribosomal protein L1 (P27150) · a predicted model of the same protein · chain A against A, TM-score 0.68
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P27150
- Elsewhere: RCSB PDB 4REO · PDBe 4REO · UniProt P27150
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.