MolNFT v1 · #105319 · protein
Crystal structure of mtip from plasmodium falciparum in complex with a peptide-fragment chimera
4R1E · Myosin a tail domain interacting protein: “Crystal structure of mtip from plasmodium falciparum in complex with a peptide-fragment chimera”. X-ray diffraction, 1 ligand (3EC). MolNFT v1 #105319 on GenesisL1: 3D structure, binding…
- PDB
- 4R1E
- Type
- protein
- Length
- 157 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Myosin a tail domain interacting protein; Myosin-a
- UniProt
- Q8I4W8, Q8IDR3
- Ligands
- 3EC
Structure
x-ray diffraction · 2 distinct chains · 60% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Myosin a tail domain interacting protein | protein | 142 | 57% helix, 8% strand | Q8I4W8 |
| B | Myosin-a | protein | 15 | 87% helix, 0% strand | Q8IDR3 |
Ligands and binding sites
- 3EC · 5-{[(2-aminoethyl)sulfanyl]methyl}furan-2-carbaldehyde · ligand · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 1049 Ų buried · 16 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 covalent (covalent ligand).
Compared structures
- 4R1E · Crystal Structure of MTIP from Plasmodium falciparum in complex with a peptide-fragment… · the same entry in another collection · chain A against A, TM-score 1.00
- Q8IDR3 · AlphaFold monomer V2.0 prediction for myosin-a (Q8IDR3) · a predicted model of the same protein · chain B against A, TM-score 0.83
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8I4W8
- Every structure of UniProt Q8IDR3
- Elsewhere: RCSB PDB 4R1E · PDBe 4R1E · UniProt Q8I4W8 · UniProt Q8IDR3
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