MolNFT v1 · #104732 · protein
X-ray crystal structure of thermocuccus kodakarensis RNA polymerase RPP4/RPO7 (RPOF/RPOE) complex
4QJF · DNA-directed RNA polymerase, subunit E': “X-ray crystal structure of thermocuccus kodakarensis RNA polymerase RPP4/RPO7 (RPOF/RPOE) complex”. X-ray diffraction, 2 pockets (best druggability 0.40). MolNFT v1 #104732 on GenesisL1: 3D…
- PDB
- 4QJF
- Type
- protein
- Length
- 308 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- DNA-directed RNA polymerase, subunit E'; DNA-directed RNA polymerase, subunit F
- UniProt
- Q5JIY4, Q5JI52
- Pockets
- 2 · best druggability 0.40
Structure
x-ray diffraction · 2 distinct chains · 31% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA-directed RNA polymerase, subunit E' | protein | 186 | 16% helix, 47% strand | Q5JIY4 |
| B | DNA-directed RNA polymerase, subunit F | protein | 122 | 56% helix, 7% strand | Q5JI52 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 106 | 0.40 | 0.76 | 19 | empty |
| 2 | 128 | 0.40 | 0.74 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 2448 Ų buried · 38 hydrogen bonds · protein-protein
Compared structures
- 4QJF · X-ray crystal structure of Thermocuccus kodakarensis RNA polymerase Rpp4/Rpo7 (RpoF/RpoE)… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5JIY4
- Every structure of UniProt Q5JI52
- Elsewhere: RCSB PDB 4QJF · PDBe 4QJF · UniProt Q5JIY4 · UniProt Q5JI52
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