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X-ray crystal structure of thermocuccus kodakarensis RNA polymerase RPP4/RPO7 (RPOF/RPOE) complex

Analyse X-ray crystal structure of thermocuccus kodakarensis RNA polymerase RPP4/RPO7… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4QJF
Type: protein
Length: 308 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: DNA-directed RNA polymerase, subunit E'; DNA-directed RNA polymerase, subunit F
UniProt: Q5JIY4, Q5JI52
Pockets: 2 · best druggability 0.40

Structure

x-ray diffraction · 2 distinct chains · 31% helix, 31% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA-directed RNA polymerase, subunit E'	protein	186	16% helix, 47% strand	Q5JIY4
B	DNA-directed RNA polymerase, subunit F	protein	122	56% helix, 7% strand	Q5JI52

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	106	0.40	0.76	19	empty
2	128	0.40	0.74	17	empty

Interfaces

1 interface between chains.

A–B · 2448 Å² buried · 38 hydrogen bonds · protein-protein

Compared structures

4QJF · X-ray crystal structure of Thermocuccus kodakarensis RNA polymerase Rpp4/Rpo7 (RpoF/RpoE)… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5JIY4
Every structure of UniProt Q5JI52
Elsewhere: RCSB PDB 4QJF · PDBe 4QJF · UniProt Q5JIY4 · UniProt Q5JI52

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