MolNFT v1 · #104421 · protein
Mtfp*: a robust and versatile host protein at 1.00 a resolution
4Q9W · GFP-like fluorescent chromoprotein CFP484: “Mtfp*: a robust and versatile host protein at 1.00 a resolution”. X-ray diffraction, 1 ligand (PIA), 6 pockets (best druggability 0.74). MolNFT v1 #104421 on GenesisL1: 3D structure…
- PDB
- 4Q9W
- Type
- protein
- Length
- 434 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- GFP-like fluorescent chromoprotein CFP484
- UniProt
- Q9U6Y3
- Ligands
- PIA
- Pockets
- 6 · best druggability 0.74
Structure
x-ray diffraction · 1 distinct chain · 4% helix, 58% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | GFP-like fluorescent chromoprotein CFP484 | protein | 217 | 4% helix, 58% strand | Q9U6Y3 |
Ligands and binding sites
- PIA · [(4Z)-2-[(1S)-1-aminoethyl]-4-(4-hydroxybenzylidene)-5-oxo-4,5-dihydro-1H-imidazol-1-yl]acetic acid · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 71 | 0.74 | 0.98 | 24 | PIA |
| 2 | 595 | 0.73 | 0.81 | 58 | empty |
| 3 | 66 | 0.73 | 0.98 | 26 | PIA |
| 4 | 58 | 0.42 | 0.82 | 19 | empty |
| 5 | 90 | 0.38 | 0.76 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 461 Ų buried · 6 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 covalent (covalent ligand).
Compared structures
- 4Q9W · mTFP*: a robust and versatile host protein at 1.00 A resolution · the same entry in another collection · chain B against B, TM-score 1.00
- Q9U6Y3 · AlphaFold monomer V2.0 prediction for GFP-like fluorescent chromoprotein CFP484 (Q9U6Y3) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9U6Y3
- Elsewhere: RCSB PDB 4Q9W · PDBe 4Q9W · UniProt Q9U6Y3
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