MolNFT v1 · #104303 · protein
Crystal structure of eal domain protein from listeria monocytogenes egd-E
4Q6J · LMO0131 protein: “Crystal structure of eal domain protein from listeria monocytogenes egd-E”. X-ray diffraction, 1 ligand (PO4), 6 pockets (best druggability 0.80). MolNFT v1 #104303 on GenesisL1: 3D structure, binding sites and…
- PDB
- 4Q6J
- Type
- protein
- Length
- 492 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- LMO0131 protein
- UniProt
- Q8YAJ4
- Ligands
- PO4
- Pockets
- 6 · best druggability 0.80
Structure
x-ray diffraction · 2 distinct chains · 46% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | LMO0131 protein | protein | 245 | 46% helix, 22% strand | Q8YAJ4 |
| B | LMO0131 protein | protein | 247 | 47% helix, 21% strand | Q8YAJ4 |
Ligands and binding sites
- PO4 · Phosphate ion · ion · 2 copies · chains A, B
- EDO · 1,2-ethanediol · additive · 13 copies · chains A, B
- GOL · Glycerol · additive · chains A
- ACY · Acetic acid · additive · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 503 | 0.80 | 0.86 | 53 | EDO |
| 2 | 556 | 0.77 | 0.83 | 55 | EDO |
| 3 | 136 | 0.48 | 0.78 | 18 | GOL |
| 4 | 104 | 0.43 | 0.78 | 17 | EDO |
| 5 | 98 | 0.41 | 0.77 | 16 | EDO |
Interfaces
1 interface between chains.
- A–B · 959 Ų buried · 13 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 15 modified (engineered).
Compared structures
- 4Q6J · Crystal Structure of EAL domain Protein from Listeria monocytogenes EGD-e · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8YAJ4
- Elsewhere: RCSB PDB 4Q6J · PDBe 4Q6J · UniProt Q8YAJ4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.