MolNFT v1 · #103987 · protein
Crystal structure of lipid phosphatase E. COLI pgpb
4PX7 · Phosphatidylglycerophosphatase: “Crystal structure of lipid phosphatase E. COLI pgpb”. X-ray diffraction, 4 pockets (best druggability 0.68). MolNFT v1 #103987 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4PX7
- Type
- protein
- Length
- 251 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phosphatidylglycerophosphatase
- EC
- 3.1.3.27, 3.6.1.27
- UniProt
- C6EFV6
- Pockets
- 4 · best druggability 0.68
Structure
x-ray diffraction · 1 distinct chain · 70% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphatidylglycerophosphatase (EC 3.1.3.27, 3.6.1.27) | protein | 251 | 70% helix, 1% strand | C6EFV6 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 451 | 0.68 | 0.79 | 45 | LDA, GOL |
| 2 | 75 | 0.52 | 0.85 | 20 | empty |
| 3 | 56 | 0.38 | 0.79 | 14 | empty |
| 4 | 78 | 0.33 | 0.74 | 22 | empty |
Modifications
Observed in the structure: 5 modified (engineered).
Compared structures
- 4PX7 · Crystal structure of lipid phosphatase E. coli PgpB · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt C6EFV6
- Elsewhere: RCSB PDB 4PX7 · PDBe 4PX7 · UniProt C6EFV6
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.