MolNFT v1 · #103475 · protein

Selenomethionine substituted structure of domain of unknown function 1792 (DUF1792)

4PHS · Putative glycosyltransferase (GALT1): “Selenomethionine substituted structure of domain of unknown function 1792 (DUF1792)”. X-ray diffraction, 1 ligand (UDP), 2 pockets (best druggability 0.78). MolNFT v1 #103475 on GenesisL1: 3D…

PDB: 4PHS
Type: protein
Length: 277 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative glycosyltransferase (GALT1)
UniProt: I1ZPA1
Ligands: UDP
Pockets: 2 · best druggability 0.78

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Putative glycosyltransferase (GALT1)	protein	277	42% helix, 16% strand	I1ZPA1

Ligands and binding sites

UDP · Uridine-5'-diphosphate · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	337	0.78	0.88	60	UDP
2	50	0.29	0.76	18	empty

Modifications

Observed in the structure: 4 modified, 1 disulfide (engineered, disulfide).

Compared structures

4PHS · Selenomethionine substituted structure of domain of unknown function 1792 (DUF1792) · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt I1ZPA1
Elsewhere: RCSB PDB 4PHS · PDBe 4PHS · UniProt I1ZPA1

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