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MolNFT v1 · #10334 · protein

Growth factor receptor-bound protein 2 (GRB2) C-terminal SH3 domain complexed with a ligand peptide (NMR, minimized mean structure)

1IO6: “Growth factor receptor-bound protein 2 (GRB2) C-terminal SH3 domain complexed with a ligand peptide (NMR…”. Solution nmr. MolNFT v1 #10334 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
1IO6
Type
protein
Length
69 residues
Chains
2
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Growth factor receptor-bound protein 2; A ligand peptide
UniProt
P62993

Structure

solution nmr · 2 distinct chains · 0% helix, 26% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AGrowth factor receptor-bound protein 2protein590% helix, 31% strandP62993
BA ligand peptideprotein100% helix, 0% strand—

Interfaces

1 interface between chains.

  • A–B · 585 Ų buried · 2 hydrogen bonds · protein-protein

Compared structures

  • 1IO6 · Growth factor receptor-bound protein 2 (GRB2) C-terminal SH3 domain complexed with a… · the same entry in another collection · chain A against A, TM-score 1.00
  • P62993 · AlphaFold monomer V2.0 prediction for growth factor receptor-bound protein 2 (P62993) · a predicted model of the same protein · chain A against A, TM-score 0.86

Analyse

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