MolNFT v1 · #103131 · protein
Structure of ribb complexed with substrate RU5P
4P77 · 3,4-dihydroxy-2-butanone 4-phosphate synthase: “Structure of ribb complexed with substrate RU5P”. X-ray diffraction, 1 ligand (5RP), 2 pockets (best druggability 0.64). MolNFT v1 #103131 on GenesisL1: 3D structure, binding sites and…
- PDB
- 4P77
- Type
- protein
- Length
- 423 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 3,4-dihydroxy-2-butanone 4-phosphate synthase
- EC
- 4.1.99.12
- UniProt
- Q9KKP2
- Ligands
- 5RP
- Pockets
- 2 · best druggability 0.64
Structure
x-ray diffraction · 2 distinct chains · 42% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 3,4-dihydroxy-2-butanone 4-phosphate synthase (EC 4.1.99.12) | protein | 214 | 41% helix, 20% strand | Q9KKP2 |
| B | 3,4-dihydroxy-2-butanone 4-phosphate synthase (EC 4.1.99.12) | protein | 209 | 43% helix, 22% strand | Q9KKP2 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 162 | 0.64 | 0.86 | 30 | 5RP |
| 2 | 106 | 0.55 | 0.84 | 25 | 5RP |
Interfaces
1 interface between chains.
- A–B · 1398 Ų buried · 14 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9KKP2
- Elsewhere: RCSB PDB 4P77 · PDBe 4P77 · UniProt Q9KKP2
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