MolNFT v1 · #102982 · protein

Structure of ephrin type-a receptor 2

4P2K: “Structure of ephrin type-a receptor 2”. X-ray diffraction, 1 pocket (best druggability 0.65). MolNFT v1 #102982 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4P2K
Type: protein
Length: 259 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ephrin type-a receptor 2
EC: 2.7.10.1
UniProt: P29317
Pockets: 1 · best druggability 0.65

Structure

x-ray diffraction · 1 distinct chain · 40% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ephrin type-a receptor 2 (EC 2.7.10.1)	protein	259	40% helix, 18% strand	P29317

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	292	0.65	0.81	37	empty

Compared structures

4P2K · Structure of Ephrin type-A receptor 2 · the same entry in another collection · chain A against A, TM-score 1.00
P29317 · AlphaFold monomer V2.0 prediction for ephrin type-a receptor 2 (P29317) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P29317
Elsewhere: RCSB PDB 4P2K · PDBe 4P2K · UniProt P29317

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