MolNFT v1 · #102949 · protein

Crystal structure of the bateman domain of murine magnesium transporter CNNM2 bound to AMP

4P1G · Metal transporter CNNM2: “Crystal structure of the bateman domain of murine magnesium transporter CNNM2 bound to AMP”. X-ray diffraction, 1 ligand (AMP), 1 pocket (best druggability 0.36). MolNFT v1 #102949 on GenesisL1: 3D…

PDB: 4P1G
Type: protein
Length: 152 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Metal transporter CNNM2
UniProt: Q3TWN3
Ligands: AMP
Pockets: 1 · best druggability 0.36

Structure

x-ray diffraction · 1 distinct chain · 39% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Metal transporter CNNM2	protein	152	39% helix, 27% strand	Q3TWN3

Ligands and binding sites

AMP · Adenosine monophosphate · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	58	0.36	0.79	13	AMP

Compared structures

4P1G · Crystal structure of the Bateman domain of murine magnesium transporter CNNM2 bound to AMP · the same entry in another collection · chain A against A, TM-score 1.00
Q3TWN3 · AlphaFold monomer V2.0 prediction for metal transporter CNNM2 (Q3TWN3) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q3TWN3
Elsewhere: RCSB PDB 4P1G · PDBe 4P1G · UniProt Q3TWN3

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.