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Crystal structure of the bateman domain of murine magnesium transporter CNNM2 bound to AMP

Analyse Crystal structure of the bateman domain of murine magnesium transporter CNNM2… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4P1G
Type: protein
Length: 152 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Metal transporter CNNM2
UniProt: Q3TWN3
Ligands: AMP
Pockets: 1 · best druggability 0.36

Structure

x-ray diffraction · 1 distinct chain · 39% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Metal transporter CNNM2	protein	152	39% helix, 27% strand	Q3TWN3

Ligands and binding sites

AMP · Adenosine monophosphate · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	58	0.36	0.79	13	AMP

Compared structures

4P1G · Crystal structure of the Bateman domain of murine magnesium transporter CNNM2 bound to AMP · the same entry in another collection · chain A against A, TM-score 1.00
Q3TWN3 · AlphaFold monomer V2.0 prediction for metal transporter CNNM2 (Q3TWN3) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q3TWN3
Elsewhere: RCSB PDB 4P1G · PDBe 4P1G · UniProt Q3TWN3

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