MolNFT v1 · #102941 · protein

Crystal structure of the chlamydomonas flagellar rabgap tbc domain.

4P17 · RABGAP/TBC protein: “Crystal structure of the chlamydomonas flagellar rabgap tbc domain.”. X-ray diffraction, 7 pockets (best druggability 0.53). MolNFT v1 #102941 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4P17
Type: protein
Length: 578 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: RABGAP/TBC protein
UniProt: A8JCA4
Pockets: 7 · best druggability 0.53

Structure

x-ray diffraction · 2 distinct chains · 67% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	RABGAP/TBC protein	protein	288	67% helix, 1% strand	A8JCA4
B	RABGAP/TBC protein	protein	290	67% helix, 1% strand	A8JCA4

Pockets

7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	222	0.53	0.77	33	empty
2	340	0.51	0.73	35	empty
3	202	0.51	0.76	26	empty
4	71	0.43	0.81	20	empty
5	115	0.43	0.76	16	empty

Interfaces

1 interface between chains.

A–B · 268 Å² buried · 2 hydrogen bonds · protein-protein

Compared structures

4P17 · Crystal structure of the Chlamydomonas flagellar RabGAP TBC domain. · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A8JCA4
Elsewhere: RCSB PDB 4P17 · PDBe 4P17 · UniProt A8JCA4

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.