Research workbench
Crystal structure of the chlamydomonas flagellar rabgap tbc domain.
Analyse Crystal structure of the chlamydomonas flagellar rabgap tbc domain. in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4P17
- Type
- protein
- Length
- 578 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RABGAP/TBC protein
- UniProt
- A8JCA4
- Pockets
- 7 · best druggability 0.53
Structure
x-ray diffraction · 2 distinct chains · 67% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RABGAP/TBC protein | protein | 288 | 67% helix, 1% strand | A8JCA4 |
| B | RABGAP/TBC protein | protein | 290 | 67% helix, 1% strand | A8JCA4 |
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 222 | 0.53 | 0.77 | 33 | empty |
| 2 | 340 | 0.51 | 0.73 | 35 | empty |
| 3 | 202 | 0.51 | 0.76 | 26 | empty |
| 4 | 71 | 0.43 | 0.81 | 20 | empty |
| 5 | 115 | 0.43 | 0.76 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 268 Ų buried · 2 hydrogen bonds · protein-protein
Compared structures
- 4P17 · Crystal structure of the Chlamydomonas flagellar RabGAP TBC domain. · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A8JCA4
- Elsewhere: RCSB PDB 4P17 · PDBe 4P17 · UniProt A8JCA4
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