MolNFT v1 · #1025 · protein
NMR structure of the fyn SH2 domain complexed with a phosphotyrosyl peptide, 22 structures
1AOU · Fyn protein-tyrosine kinase: “NMR structure of the fyn SH2 domain complexed with a phosphotyrosyl peptide, 22 structures”. Solution nmr. MolNFT v1 #1025 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1AOU
- Type
- protein
- Length
- 117 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fyn protein-tyrosine kinase; Phosphotyrosyl peptide
- EC
- 2.7.1.112
- UniProt
- P06241, P03079
Structure
solution nmr · 2 distinct chains · 16% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| F | Fyn protein-tyrosine kinase (EC 2.7.1.112) | protein | 106 | 18% helix, 26% strand | P06241 |
| P | Phosphotyrosyl peptide | protein | 11 | 0% helix, 0% strand | P03079 |
Interfaces
1 interface between chains.
- F–P · 499 Ų buried · 9 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 modified (phosphorylation).
Compared structures
- 1AOU · NMR structure of the fyn SH2 domain complexed with a phosphotyrosyl peptide, 22 structures · the same entry in another collection · chain F against F, TM-score 1.00
- P06241 · AlphaFold monomer V2.0 prediction for tyrosine-protein kinase fyn (P06241) · a predicted model of the same protein · chain F against A, TM-score 0.79
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P06241
- Every structure of UniProt P03079
- Elsewhere: RCSB PDB 1AOU · PDBe 1AOU · UniProt P06241 · UniProt P03079
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