MolNFT v1 · #102357 · protein
Crystal structure of W741L-ar-lbd
4OJB · Androgen receptor: “Crystal structure of W741L-ar-lbd”. X-ray diffraction, 1 ligand (198), 2 pockets (best druggability 0.84). MolNFT v1 #102357 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4OJB
- Type
- protein
- Length
- 240 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Androgen receptor
- UniProt
- P10275
- Ligands
- 198
- Pockets
- 2 · best druggability 0.84
Structure
x-ray diffraction · 1 distinct chain · 69% helix, 5% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Androgen receptor | protein | 240 | 69% helix, 5% strand | P10275 |
Ligands and binding sites
- 198 · R-bicalutamide · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 194 | 0.84 | 0.97 | 27 | 198 |
| 2 | 144 | 0.62 | 0.85 | 26 | empty |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P10275
- Elsewhere: RCSB PDB 4OJB · PDBe 4OJB · UniProt P10275
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.