MolNFT v1 · #101721 · protein

Crystal structure of the titin a-band domain A3

4O00: “Crystal structure of the titin a-band domain A3”. X-ray diffraction, 1 pocket (best druggability 0.45). MolNFT v1 #101721 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4O00
Type: protein
Length: 206 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Titin
EC: 2.7.11.1
UniProt: Q8WZ42
Pockets: 1 · best druggability 0.45

Structure

x-ray diffraction · 2 distinct chains · 0% helix, 43% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Titin (EC 2.7.11.1)	protein	102	0% helix, 43% strand	Q8WZ42
B	Titin (EC 2.7.11.1)	protein	104	0% helix, 42% strand	Q8WZ42

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	96	0.45	0.80	18	empty

Interfaces

1 interface between chains.

A–B · 577 Å² buried · 3 hydrogen bonds · protein-protein

Compared structures

4O00 · Crystal structure of the Titin A-band domain A3 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8WZ42
Elsewhere: RCSB PDB 4O00 · PDBe 4O00 · UniProt Q8WZ42

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.