MolNFT v1 · #101557 · protein

Crystal structure of a glycosynthase mutant (D233Q) of endos, an endo- beta-N-acetyl-glucosaminidase from streptococcus pyogenes

4NUZ · Endo-beta-N-acetylglucosaminidase F2: “Crystal structure of a glycosynthase mutant (D233Q) of endos, an endo- beta-N-acetyl-glucosaminidase from…”. X-ray diffraction, 1 ligand (CA), 7 pockets (best druggability 0.60). MolNFT v1…

PDB: 4NUZ
Type: protein
Length: 888 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Endo-beta-N-acetylglucosaminidase F2
EC: 3.2.1.96
UniProt: Q48WW7
Ligands: CA
Pockets: 7 · best druggability 0.60

Structure

x-ray diffraction · 1 distinct chain · 29% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Endo-beta-N-acetylglucosaminidase F2 (EC 3.2.1.96)	protein	888	29% helix, 23% strand	Q48WW7

Ligands and binding sites

CA · Calcium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	297	0.60	0.78	43	empty
2	202	0.53	0.78	46	empty
3	198	0.46	0.74	33	empty
4	152	0.44	0.75	21	empty
5	85	0.32	0.73	14	empty

Compared structures

4NUZ · Crystal structure of a glycosynthase mutant (D233Q) of EndoS, an… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q48WW7
Elsewhere: RCSB PDB 4NUZ · PDBe 4NUZ · UniProt Q48WW7

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