MolNFT v1 · #101401 · protein

Structure of ZN(II)-bound metallo-beta-lactamse vim-2 from pseudomonas aeruginosa

4NQ2 · Beta-lactamase class B vim-2: “Structure of ZN(II)-bound metallo-beta-lactamse vim-2 from pseudomonas aeruginosa”. X-ray diffraction, 1 ligand (ZN), 1 pocket (best druggability 0.40). MolNFT v1 #101401 on GenesisL1: 3D structure…

PDB: 4NQ2
Type: protein
Length: 230 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Beta-lactamase class B vim-2
EC: 3.5.2.6
UniProt: Q9K2N0
Ligands: ZN
Pockets: 1 · best druggability 0.40

Structure

x-ray diffraction · 1 distinct chain · 27% helix, 29% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Beta-lactamase class B vim-2 (EC 3.5.2.6)	protein	230	27% helix, 29% strand	Q9K2N0

Ligands and binding sites

ZN · Zinc ion · metal · 3 copies · chains A
ACT · Acetate ion · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	104	0.40	0.77	19	ZN

Compared structures

4NQ2 · Structure of Zn(II)-bound metallo-beta-lactamse VIM-2 from Pseudomonas aeruginosa · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9K2N0
Elsewhere: RCSB PDB 4NQ2 · PDBe 4NQ2 · UniProt Q9K2N0

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