MolNFT v1 · #101289 · protein
2.60 ångström resolution crystal structure of putative ribose 5- phosphate isomerase from toxoplasma gondii ME49 in complex with dl- malic acid
4NML · Ribulose 5-phosphate isomerase: “2.60 ångström resolution crystal structure of putative ribose 5- phosphate isomerase from toxoplasma gondii…”. X-ray diffraction, 2 ligands (MLT, CL), 1 pocket (best druggability 0.43). MolNFT v1…
- PDB
- 4NML
- Type
- protein
- Length
- 250 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ribulose 5-phosphate isomerase
- EC
- 5.3.1.6
- UniProt
- S8GQK2
- Ligands
- MLT, CL
- Pockets
- 1 · best druggability 0.43
Structure
x-ray diffraction · 1 distinct chain · 33% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ribulose 5-phosphate isomerase (EC 5.3.1.6) | protein | 250 | 33% helix, 26% strand | S8GQK2 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 61 | 0.43 | 0.83 | 20 | CL, MLT |
Modifications
Observed in the structure: 6 modified (engineered, artifact).
Compared structures
- 4NML · 2.60 Angstrom resolution crystal structure of putative ribose 5-phosphate isomerase from… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt S8GQK2
- Elsewhere: RCSB PDB 4NML · PDBe 4NML · UniProt S8GQK2
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