MolNFT v1 · #101206 · protein
Crystal structure of the periplasmic alginate epimerase algg D317A mutant
4NK8 · POLY(BETA-D-mannuronate) C5 epimerase: “Crystal structure of the periplasmic alginate epimerase algg D317A mutant”. X-ray diffraction, 1 pocket (best druggability 0.31). MolNFT v1 #101206 on GenesisL1: 3D structure, binding sites…
- PDB
- 4NK8
- Type
- protein
- Length
- 424 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- POLY(BETA-D-mannuronate) C5 epimerase
- EC
- 5.1.3.-
- UniProt
- Q887Q3
- Pockets
- 1 · best druggability 0.31
Structure
x-ray diffraction · 1 distinct chain · 9% helix, 42% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | POLY(BETA-D-mannuronate) C5 epimerase (EC 5.1.3.-) | protein | 424 | 9% helix, 42% strand | Q887Q3 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 89 | 0.31 | 0.73 | 18 | empty |
Modifications
Observed in the structure: 7 modified (methylation).
Compared structures
- 4NK8 · Crystal Structure of the periplasmic alginate epimerase AlgG D317A mutant · the same entry in another collection · chain A against A, TM-score 1.00
- Q887Q3 · AlphaFold monomer V2.0 prediction for mannuronan C5-epimerase (Q887Q3) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q887Q3
- Elsewhere: RCSB PDB 4NK8 · PDBe 4NK8 · UniProt Q887Q3
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