MolNFT v1 · #100973 · protein

X-ray structure of a mutant (T61D) of calexcitin - a neuronal calcium- signalling protein

4NDB: “X-ray structure of a mutant (T61D) of calexcitin - a neuronal calcium- signalling protein”. X-ray diffraction, 1 ligand (CA), 3 pockets (best druggability 0.76). MolNFT v1 #100973 on GenesisL1: 3D structure, binding sites and…

PDB: 4NDB
Type: protein
Length: 371 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Calexcitin
UniProt: O76764
Ligands: CA
Pockets: 3 · best druggability 0.76

Structure

x-ray diffraction · 2 distinct chains · 65% helix, 4% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Calexcitin	protein	187	65% helix, 3% strand	O76764
B	Calexcitin	protein	184	65% helix, 4% strand	O76764

Ligands and binding sites

CA · Calcium ion · metal · 6 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	117	0.76	0.95	22	empty
2	331	0.62	0.78	39	empty
3	61	0.31	0.75	10	empty

Interfaces

1 interface between chains.

A–B · 117 Å² buried · 0 hydrogen bonds · protein-protein

Compared structures

4NDB · X-ray structure of a mutant (T61D) of calexcitin - a neuronal calcium-signalling protein · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O76764
Elsewhere: RCSB PDB 4NDB · PDBe 4NDB · UniProt O76764

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.