MolNFT v1 · #100851 · protein
Crystal structure of phosphatidyl mannosyltransferase pima
4N9W · GDP-mannose-dependent alpha-(1-2)-phosphatidylinositol…: “Crystal structure of phosphatidyl mannosyltransferase pima”. X-ray diffraction, 1 ligand (GDP), 2 pockets (best druggability 0.73). MolNFT v1 #100851 on GenesisL1: 3D…
- PDB
- 4N9W
- Type
- protein
- Length
- 360 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- GDP-mannose-dependent alpha-(1-2)-phosphatidylinositol mannosyltransferase
- EC
- 2.4.1.57
- UniProt
- A0QWG6
- Ligands
- GDP
- Pockets
- 2 · best druggability 0.73
Structure
x-ray diffraction · 1 distinct chain · 46% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | GDP-mannose-dependent alpha-(1-2)-phosphatidylinositol mannosyltransferase (EC 2.4.1.57) | protein | 360 | 46% helix, 19% strand | A0QWG6 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 694 | 0.73 | 0.79 | 66 | GDP |
| 2 | 116 | 0.37 | 0.73 | 23 | empty |
Compared structures
- 4N9W · Crystal structure of phosphatidyl mannosyltransferase PimA · the same entry in another collection · chain A against A, TM-score 1.00
- A0QWG6 · AlphaFold monomer V2.0 prediction for phosphatidyl-myo-inositol mannosyltransferase… · a predicted model of the same protein · chain A against A, TM-score 0.91
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0QWG6
- Elsewhere: RCSB PDB 4N9W · PDBe 4N9W · UniProt A0QWG6
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