MolNFT v1 · #100360 · protein
Crystal structure of biotin carboxylase from haemophilus influenzae in complex with phosphonoacetamide
4MV6: “Crystal structure of biotin carboxylase from haemophilus influenzae in complex with phosphonoacetamide”. X-ray diffraction, 1 ligand (PCT), 1 pocket (best druggability 0.61). MolNFT v1 #100360 on GenesisL1: 3D structure, binding…
- PDB
- 4MV6
- Type
- protein
- Length
- 412 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Biotin carboxylase
- EC
- 6.3.4.14, 6.4.1.2
- UniProt
- P43873
- Ligands
- PCT
- Pockets
- 1 · best druggability 0.61
Structure
x-ray diffraction · 1 distinct chain · 35% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Biotin carboxylase (EC 6.3.4.14, 6.4.1.2) | protein | 412 | 35% helix, 27% strand | P43873 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 424 | 0.61 | 0.76 | 50 | PCT |
Compared structures
- 4MV6 · Crystal Structure of Biotin Carboxylase from Haemophilus influenzae in Complex with… · the same entry in another collection · chain A against A, TM-score 1.00
- P43873 · AlphaFold monomer V2.0 prediction for biotin carboxylase (P43873) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P43873
- Elsewhere: RCSB PDB 4MV6 · PDBe 4MV6 · UniProt P43873
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