MolNFT v1 · #100285 · protein

Crystal structure of the neisseria gonorrhoeae mtrd inner membrane multidrug efflux pump

4MT1 · Drug efflux protein: “Crystal structure of the neisseria gonorrhoeae mtrd inner membrane multidrug efflux pump”. X-ray diffraction, 13 pockets (best druggability 0.74). MolNFT v1 #100285 on GenesisL1: 3D structure, binding sites and…

PDB: 4MT1
Type: protein
Length: 1,023 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Drug efflux protein
UniProt: D1E405
Pockets: 13 · best druggability 0.74

Structure

x-ray diffraction · 1 distinct chain · 51% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Drug efflux protein	protein	1023	51% helix, 18% strand	D1E405

Pockets

13 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	391	0.74	0.85	74	empty
2	624	0.73	0.80	81	empty
3	220	0.73	0.88	39	empty
4	246	0.68	0.84	45	empty
5	152	0.55	0.81	31	empty

Compared structures

4MT1 · Crystal Structure of the Neisseria gonorrhoeae MtrD Inner Membrane Multidrug Efflux Pump · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt D1E405
Elsewhere: RCSB PDB 4MT1 · PDBe 4MT1 · UniProt D1E405

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.