MolNFT v1 · #542317 · protein
AlphaFold monomer V2.0 prediction for zz-type zinc finger-containing protein 3 (Q8IYH5)
Q8IYH5: “AlphaFold monomer V2.0 prediction for zz-type zinc finger-containing protein 3 (Q8IYH5)”. 4 pockets (best druggability 0.43). MolNFT v1 #542317 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8IYH5
- Type
- protein
- Length
- 903 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xd640e0Ab714Ec43DD946c544144F9045dd7C9133
- Molecule
- Zz-type zinc finger-containing protein 3
- UniProt
- Q8IYH5
- Pockets
- 4 · best druggability 0.43
Structure
1 distinct chain · 17% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Zz-type zinc finger-containing protein 3 | protein | 903 | 17% helix, 2% strand | Q8IYH5 |
Pockets
4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 182 | 0.43 | 0.73 | 34 | empty |
| 2 | 76 | 0.36 | 0.77 | 12 | empty |
| 3 | 52 | 0.36 | 0.79 | 14 | empty |
| 4 | 82 | 0.34 | 0.74 | 14 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 6E86 · Solution structure of ZZZ3 zz domain in complex with histone H3K4AC peptide · an experimental structure of the same protein · chain A against B, TM-score 0.07
- 6E86 · Solution structure of ZZZ3 ZZ domain in complex with histone H3K4ac peptide · an experimental structure of the same protein · chain A against B, TM-score 0.07
- 2YUM · Solution structure of the Myb-like DNA-binding domain of human ZZZ3 protein · an experimental structure of the same protein · chain A against A, TM-score 0.07
- 2YUM · Solution structure of the myb-like DNA-binding domain of human ZZZ3 protein · an experimental structure of the same protein · chain A against A, TM-score 0.07
- 6E83 · Solution structure of ZZZ3 zz domain in complex with histone H3 tail · an experimental structure of the same protein · chain A against B, TM-score 0.07
- 6E83 · Solution structure of ZZZ3 ZZ domain in complex with histone H3 tail · an experimental structure of the same protein · chain A against B, TM-score 0.07
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8IYH5
- Elsewhere: UniProt Q8IYH5 · AlphaFold DB Q8IYH5
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