MolNFT v1 · #541960 · protein
AlphaFold monomer V2.0 prediction for tight junction protein zo-3 (O95049)
O95049: “AlphaFold monomer V2.0 prediction for tight junction protein zo-3 (O95049)”. 9 pockets (best druggability 0.73). MolNFT v1 #541960 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O95049
- Type
- protein
- Length
- 919 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xA528629DC5BcCeBDa9059C9f45aab2F210565E6f
- Molecule
- Tight junction protein zo-3
- UniProt
- O95049
- Pockets
- 9 · best druggability 0.73
Structure
1 distinct chain · 20% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tight junction protein zo-3 | protein | 919 | 20% helix, 20% strand | O95049 |
Pockets
9 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 711 | 0.73 | 0.79 | 73 | empty |
| 2 | 159 | 0.55 | 0.81 | 25 | empty |
| 3 | 243 | 0.55 | 0.77 | 35 | empty |
| 4 | 126 | 0.54 | 0.82 | 22 | empty |
| 5 | 137 | 0.43 | 0.76 | 26 | empty |
Compared structures
- 3KFV · Crystal structure of the SH3-kinase fragment of tight junction protein 3 (TJP3) in… · an experimental structure of the same protein · chain A against A, TM-score 0.26
- 3KFV · Crystal structure of the SH3-kinase fragment of tight junction protein 3 (TJP3) in… · an experimental structure of the same protein · chain A against A, TM-score 0.26
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O95049
- Elsewhere: UniProt O95049 · AlphaFold DB O95049
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